Pub. Date : 2007 Feb
PMID : 17251462
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: UV irradiation-induced apoptosis through apoptosis signal-regulating kinase 1 (ASK1) and MAKK4 (SEK1) upstream from JNK was caffeine sensitive. | Caffeine | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 2 | RESULTS: UV irradiation-induced apoptosis through apoptosis signal-regulating kinase 1 (ASK1) and MAKK4 (SEK1) upstream from JNK was caffeine sensitive. | Caffeine | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 3 | CONCLUSIONS: UV irradiation stress-induced activation of the ASK1-SEK1-JNK signaling pathway leading to apoptosis is a caffeine-sensitive process, and caffeine, as a multifunctional agent in cells, can specifically interact with the pathway to protect against apoptosis. | Caffeine | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 4 | CONCLUSIONS: UV irradiation stress-induced activation of the ASK1-SEK1-JNK signaling pathway leading to apoptosis is a caffeine-sensitive process, and caffeine, as a multifunctional agent in cells, can specifically interact with the pathway to protect against apoptosis. | Caffeine | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |