Title : Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase.

Pub. Date : 2006 Mar 17

PMID : 17163649






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The biosynthetic assembly line producing the toxic cyclic peptide, microcystin, contains an adenylation-peptidyl carrier protein didomain (A-PCP) at the N-terminus of the initiator module McyG (295 kDa) that has been postulated to activate and load the starter unit phenylacetate for formation of the unusual aromatic beta-amino acid residue, Adda, before subsequent extension. microcystin adducin 1 Homo sapiens