Title : Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway.

Pub. Date : 2006 Aug

PMID : 16835249






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Celecoxib, but not other COX-2 inhibitors such as nimesulid, prevented myelin oligodendrocyte glycoprotein (MOG) induced EAE when administrated orally on the day of disease induction. Celecoxib myelin oligodendrocyte glycoprotein Mus musculus
2 Celecoxib, but not other COX-2 inhibitors such as nimesulid, prevented myelin oligodendrocyte glycoprotein (MOG) induced EAE when administrated orally on the day of disease induction. Celecoxib myelin oligodendrocyte glycoprotein Mus musculus
3 In celecoxib-treated mice, interferon-gamma (IFN-gamma) production from MOG-specific T cells was reduced and MOG-specific IgG1 was elevated compared with vehicle-treated mice. Celecoxib myelin oligodendrocyte glycoprotein Mus musculus
4 In celecoxib-treated mice, interferon-gamma (IFN-gamma) production from MOG-specific T cells was reduced and MOG-specific IgG1 was elevated compared with vehicle-treated mice. Celecoxib myelin oligodendrocyte glycoprotein Mus musculus