Title : Evidence for pyroglutamyl peptidase I and prolyl endopeptidase activities in the rat insulinoma cell line RINm 5F: lack of relationship with TRH metabolism.

Pub. Date : 1991 Jul 24

PMID : 1681421






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Gel filtration chromatography on Sephadex G100 shows that PGP I and PE activity have an apparent molecular mass of about 18 kDa and 57 kDa, respectively. sephadex pyroglutamyl-peptidase I Rattus norvegicus
2 inhibitor (Z-Gly-Pro-CHN2) at 5 x 10(-7) M, both cell PGP I and PE activities are inhibited. N-benzyloxycarbonylglycyl-proline diazomethyl ketone pyroglutamyl-peptidase I Rattus norvegicus