Title : Inhibitors of metabolic reactions. Scope and limitation of acyl-CoA-analogue CoA-thioethers.

Pub. Date : 1991 Jun 15

PMID : 1675605






3 Functional Relationships(s)
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1 Previously suggested roles of S-carboxymethyl-CoA, an acetyl-CoA-related inhibitor of citrate synthase, are discussed in the light of new experimental data. carboxymethyl-coenzyme A citrate synthase Homo sapiens
2 S-Acetyl, S-propionyl and S-carboxymethyl derivatives of 1,N6-etheno-CoA loose the high affinity of their CoA-counterparts to citrate synthase, probably because the ethylene group prevents proper binding to the enzyme. 1,n6-etheno-coa citrate synthase Homo sapiens
3 S-Acetyl, S-propionyl and S-carboxymethyl derivatives of 1,N6-etheno-CoA loose the high affinity of their CoA-counterparts to citrate synthase, probably because the ethylene group prevents proper binding to the enzyme. ethylene citrate synthase Homo sapiens