Title : A facile, general synthesis of 3,4-difluoro-6-substituted-2-pyrones.

Pub. Date : 2006 May 12

PMID : 16674060






3 Functional Relationships(s)
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1 Reaction of (2E)-2,3-difluoro-3-iodoacrylic acid with a variety of terminal acetylenes under cocatalysis of PdCl2(PPh3)2 and CuI gave difluorinated 2-pyrones as the sole product in good yields. (2e)-2,3-difluoro-3-iodoacrylic acid phosducin like 2 Homo sapiens
2 Reaction of (2E)-2,3-difluoro-3-iodoacrylic acid with a variety of terminal acetylenes under cocatalysis of PdCl2(PPh3)2 and CuI gave difluorinated 2-pyrones as the sole product in good yields. Alkynes phosducin like 2 Homo sapiens
3 Reaction of (2E)-2,3-difluoro-3-iodoacrylic acid with a variety of terminal acetylenes under cocatalysis of PdCl2(PPh3)2 and CuI gave difluorinated 2-pyrones as the sole product in good yields. difluorinated 2-pyrones phosducin like 2 Homo sapiens