Title : Impairment of lower jaw growth in developing zebrafish exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and reduced hedgehog expression.

Pub. Date : 2006 Jun 15

PMID : 16580747






3 Functional Relationships(s)
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1 Moreover, TCDD exposure caused downregulation of shha and shhb in a manner dependent on aryl hydrocarbon receptor 2 (ahr2). Polychlorinated Dibenzodioxins aryl hydrocarbon receptor 2 Danio rerio
2 Moreover, TCDD exposure caused downregulation of shha and shhb in a manner dependent on aryl hydrocarbon receptor 2 (ahr2). Polychlorinated Dibenzodioxins aryl hydrocarbon receptor 2 Danio rerio
3 Taken together, our data suggest that Ahr2-mediated downregulation of Hh signaling, leading to a failure of cell proliferation, contributes to TCDD induced inhibition of lower jaw growth. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor 2 Danio rerio