Title : The tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junction proteins.

Pub. Date : 1991 Oct

PMID : 1656230






2 Functional Relationships(s)
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1 Within 5 min of TPA treatment, the alpha 1 protein became rapidly phosphorylated on serine residues and its expression was dramatically reduced by 24 h. The beta 2 protein, after an initial increase in expression, was also significantly reduced 24 h after treatment with TPA. Tetradecanoylphorbol Acetate hemoglobin, beta adult minor chain Mus musculus
2 Within 5 min of TPA treatment, the alpha 1 protein became rapidly phosphorylated on serine residues and its expression was dramatically reduced by 24 h. The beta 2 protein, after an initial increase in expression, was also significantly reduced 24 h after treatment with TPA. Tetradecanoylphorbol Acetate hemoglobin, beta adult minor chain Mus musculus