Title : Deciphering the structural framework of glycine receptor anchoring by gephyrin.

Pub. Date : 2006 Mar 22

PMID : 16511563






3 Functional Relationships(s)
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1 Structure-guided mutagenesis followed by in vitro binding and in vivo colocalization assays demonstrate that a hydrophobic interaction formed by Phe 330 of gephyrin and Phe 398 and Ile 400 of the GlyR beta-loop is crucial for binding. Phenylalanine gephyrin Homo sapiens
2 Structure-guided mutagenesis followed by in vitro binding and in vivo colocalization assays demonstrate that a hydrophobic interaction formed by Phe 330 of gephyrin and Phe 398 and Ile 400 of the GlyR beta-loop is crucial for binding. Phenylalanine gephyrin Homo sapiens
3 Structure-guided mutagenesis followed by in vitro binding and in vivo colocalization assays demonstrate that a hydrophobic interaction formed by Phe 330 of gephyrin and Phe 398 and Ile 400 of the GlyR beta-loop is crucial for binding. Isoleucine gephyrin Homo sapiens