Title : Carrier-mediated hepatic uptake of a novel nonrenal excretion type uric acid generation inhibitor, Y-700.

Pub. Date : 2006 Feb

PMID : 16369928






1 Functional Relationships(s)
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1 Uptake of Y-700 by sinusoidal membrane transporters, such as organic anion transporter (Oat) 2 and organic anion transporting polypeptide (OATP)-B, OATP-C, OATP-8, and Oatp1, could not be detected although uptake of Y-700 in the oocytes expressing sodium/taurocholate cotransporting polypeptide (NTCP) was slightly observed. 1-(3-cyano-4-neopentyloxyphenyl)pyrazole-4-carboxylic acid ornithine aminotransferase pseudogene 1 Homo sapiens