Title : Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins.

Pub. Date : 2006 Feb 10

PMID : 16343532






1 Functional Relationships(s)
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1 A previous crystal structure of a microcystin bound to the catalytic subunit of protein phosphatase-1 (PP-1c) showed distinct changes in the active site region when compared with protein phosphatase-1 structures bound to other toxins. microcystin protein phosphatase 1 catalytic subunit gamma Homo sapiens