Pub. Date : 1992 Apr 2
PMID : 1631796
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of tissue factor synthesis in human umbilical vein endothelial cells involves protein kinase C. Incubation of human umbilical vein endothelial cells with one of the following compounds: endotoxin, recombinant interleukin-1 beta, recombinant tumor necrosis factor alpha, allogenic lymphocyte subpopulations or phorbol ester resulted in significant induction of tissue factor synthesis. | Phorbol Esters | coagulation factor III, tissue factor | Homo sapiens |
| 2 | Two different inhibitors of protein kinase C, H7 and sphingosine, inhibited tissue factor synthesis at concentrations which did not depress protein synthesis in general, suggesting that protein kinase C is involved in the processes leading to tissue factor synthesis. | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine | coagulation factor III, tissue factor | Homo sapiens |
| 3 | Two different inhibitors of protein kinase C, H7 and sphingosine, inhibited tissue factor synthesis at concentrations which did not depress protein synthesis in general, suggesting that protein kinase C is involved in the processes leading to tissue factor synthesis. | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine | coagulation factor III, tissue factor | Homo sapiens |
| 4 | Two different inhibitors of protein kinase C, H7 and sphingosine, inhibited tissue factor synthesis at concentrations which did not depress protein synthesis in general, suggesting that protein kinase C is involved in the processes leading to tissue factor synthesis. | Sphingosine | coagulation factor III, tissue factor | Homo sapiens |
| 5 | Two different inhibitors of protein kinase C, H7 and sphingosine, inhibited tissue factor synthesis at concentrations which did not depress protein synthesis in general, suggesting that protein kinase C is involved in the processes leading to tissue factor synthesis. | Sphingosine | coagulation factor III, tissue factor | Homo sapiens |
| 6 | Cells down-regulated for the tissue factor response to TPA responded essentially normally to endotoxin and interleukin-1 with regard to tissue factor synthesis. | Tetradecanoylphorbol Acetate | coagulation factor III, tissue factor | Homo sapiens |
| 7 | Cells down-regulated for the tissue factor response to TPA responded essentially normally to endotoxin and interleukin-1 with regard to tissue factor synthesis. | Tetradecanoylphorbol Acetate | coagulation factor III, tissue factor | Homo sapiens |