Title : Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats.

Pub. Date : 2006 Mar

PMID : 16301337






1 Functional Relationships(s)
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1 In whole-cell electrophysiological assays, CDA54 blocked the inactivated states of hNa(V)1.7 and hNa(V)1.8, two channels of the peripheral nervous system implicated in nociceptive transmission, with affinities of 0.25 and 0.18 microM, respectively. cda54 sodium voltage-gated channel alpha subunit 9 Homo sapiens