Title : Deletion of the membrane anchoring region of tissue factor abolishes autoactivation of factor VII but not cofactor function. Analysis of a mutant with a selective deficiency in activity.

Pub. Date : 1992 Jul 15

PMID : 1629232






1 Functional Relationships(s)
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1 The results strongly suggest that the phospholipid anchoring region of tissue factor is essential for autoactivation and beneficial for factor Xa-catalyzed activation of 125I-factor VII. Phospholipids coagulation factor III, tissue factor Homo sapiens