Pub. Date : 2006 Jan
PMID : 16236795
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The asymmetric localization of Kar9p to one spindle pole body (SPB) and microtubule (MT) plus ends requires Cdc28p. | cdc28p | Kar9p | Saccharomyces cerevisiae S288C |
| 2 | In the absence of Bik1p, Kar9p localization is not restricted to the daughter-bound SPB, but it is instead found on both SPBs. | sleep-promoting factor B | Kar9p | Saccharomyces cerevisiae S288C |
| 3 | The binding site of Clb5p on Kar9p maps to a short region within the basic domain of Kar9p that contains a conserved phosphorylation site, serine 496. | Serine | Kar9p | Saccharomyces cerevisiae S288C |
| 4 | The binding site of Clb5p on Kar9p maps to a short region within the basic domain of Kar9p that contains a conserved phosphorylation site, serine 496. | Serine | Kar9p | Saccharomyces cerevisiae S288C |
| 5 | Consistent with this, Kar9p is found on both SPBs in clb5delta mutants at a frequency comparable with that seen in kar9-S496A strains. | sleep-promoting factor B | Kar9p | Saccharomyces cerevisiae S288C |
| 6 | Together, these data suggest that Bik1p promotes the phosphorylation of Kar9p on serine 496, which affects its asymmetric localization to one SPB and associated cytoplasmic MTs. | Serine | Kar9p | Saccharomyces cerevisiae S288C |