Title : Pyruvate decarboxylase encoded by the PDC1 gene contributes, at least partially, to the decarboxylation of alpha-ketoisocaproate for isoamyl alcohol formation in Saccharomyces cerevisiae.

Pub. Date : 2001

PMID : 16233064






4 Functional Relationships(s)
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1 Pyruvate decarboxylase encoded by the PDC1 gene contributes, at least partially, to the decarboxylation of alpha-ketoisocaproate for isoamyl alcohol formation in Saccharomyces cerevisiae. isopentyl alcohol indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C
2 Genetic analysis showed that the activity of alpha-KIC decarboxylase and production of isoamyl alcohol partially decreased in a pdc1 null mutant and increased in a transformant with a multi-copy plasmid carrying the PDC1 gene. isopentyl alcohol indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C
3 Genetic analysis showed that the activity of alpha-KIC decarboxylase and production of isoamyl alcohol partially decreased in a pdc1 null mutant and increased in a transformant with a multi-copy plasmid carrying the PDC1 gene. isopentyl alcohol indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C
4 These results indicate that pyruvate decarboxylase encoded by the PDC1 gene contributes, at least partially, to the decarboxylation of alpha-KIC for isoamyl alcohol formation. isopentyl alcohol indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C