Title : Metabotropic P2Y1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons.

Pub. Date : 2005 Oct 3

PMID : 16181623






2 Functional Relationships(s)
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1 Whole-cell patch-clamp recordings from cultured rat dorsal root ganglion neurons demonstrated that the P2Y1 receptor agonists adenosine 5"-O-2-thiodiphosphate (ADP-beta-S) and 2-methylthio adenosine 5"-diphosphate (2-MeSADP) inhibit the alpha,beta-methylene adenosine 5"-triphosphate (alpha,beta-meATP)-induced P2X3 receptor-currents. adenosine 5'-O-(2-thiodiphosphate) purinergic receptor P2Y1 Rattus norvegicus
2 Whole-cell patch-clamp recordings from cultured rat dorsal root ganglion neurons demonstrated that the P2Y1 receptor agonists adenosine 5"-O-2-thiodiphosphate (ADP-beta-S) and 2-methylthio adenosine 5"-diphosphate (2-MeSADP) inhibit the alpha,beta-methylene adenosine 5"-triphosphate (alpha,beta-meATP)-induced P2X3 receptor-currents. adenosine 5'-O-(2-thiodiphosphate) purinergic receptor P2Y1 Rattus norvegicus