Pub. Date : 1992
PMID : 1614286
16 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | Methoxyhydroxyphenylglycol | interleukin 1 complex | Mus musculus |
| 2 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | Tryptophan | interleukin 1 complex | Mus musculus |
| 3 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | Tryptophan | interleukin 1 complex | Mus musculus |
| 4 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | norepinephrine catabolite | interleukin 1 complex | Mus musculus |
| 5 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | norepinephrine catabolite | interleukin 1 complex | Mus musculus |
| 6 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | Methoxyhydroxyphenylglycol | interleukin 1 complex | Mus musculus |
| 7 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | Methoxyhydroxyphenylglycol | interleukin 1 complex | Mus musculus |
| 8 | Interleukin-1 (IL-1) has been shown to activate the hypothalamic-pituitary-adrenal (HPA) axis, and to elevate cerebral concentrations of tryptophan and the norepinephrine catabolite, 3-methoxy,4-hydroxyphenylethyleneglycol (MHPG). | Methoxyhydroxyphenylglycol | interleukin 1 complex | Mus musculus |
| 9 | Eicosanoids have been shown to be involved in a number of the effects of IL-1, but their role in the activation of the HPA axis is controversial. | Eicosanoids | interleukin 1 complex | Mus musculus |
| 10 | However, the cyclo-oxygenase inhibitor, diclofenac, did attenuate the IL-1-induced elevation of plasma corticosterone and the neurochemical changes. | Diclofenac | interleukin 1 complex | Mus musculus |
| 11 | However, the cyclo-oxygenase inhibitor, diclofenac, did attenuate the IL-1-induced elevation of plasma corticosterone and the neurochemical changes. | Corticosterone | interleukin 1 complex | Mus musculus |
| 12 | To resolve the conflicting data on the effect of indomethacin on the IL-1-induced elevation of plasma concentration, we studied the effects of indomethacin on the response to IL-1 injected intravenously (IV). | Indomethacin | interleukin 1 complex | Mus musculus |
| 13 | To resolve the conflicting data on the effect of indomethacin on the IL-1-induced elevation of plasma concentration, we studied the effects of indomethacin on the response to IL-1 injected intravenously (IV). | Indomethacin | interleukin 1 complex | Mus musculus |
| 14 | By contrast with the response to IP IL-1, that to IV IL-1 was attenuated by indomethacin. | Indomethacin | interleukin 1 complex | Mus musculus |
| 15 | Forty min following IP IL-1, the corticosterone response to IL-1 was markedly attenuated. | Corticosterone | interleukin 1 complex | Mus musculus |
| 16 | Forty min following IP IL-1, the corticosterone response to IL-1 was markedly attenuated. | Corticosterone | interleukin 1 complex | Mus musculus |