Pub. Date : 2005 Aug 16
PMID : 16087880
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Epithelial membrane protein-1 is a biomarker of gefitinib resistance. | Gefitinib | epithelial membrane protein 1 | Homo sapiens |
| 2 | We describe a molecular resistance biomarker to gefitinib, epithelial membrane protein-1 (EMP-1). | Gefitinib | epithelial membrane protein 1 | Homo sapiens |
| 3 | We describe a molecular resistance biomarker to gefitinib, epithelial membrane protein-1 (EMP-1). | Gefitinib | epithelial membrane protein 1 | Homo sapiens |
| 4 | EMP-1 was identified as a surface biomarker whose expression correlated with acquisition of gefitinib resistance. | Gefitinib | epithelial membrane protein 1 | Homo sapiens |
| 5 | EMP-1 expression was further correlated with lack of complete or partial response to gefitinib in lung cancer patient samples as well as clinical progression to secondary gefitinib resistance. | Gefitinib | epithelial membrane protein 1 | Homo sapiens |
| 6 | EMP-1 expression was further correlated with lack of complete or partial response to gefitinib in lung cancer patient samples as well as clinical progression to secondary gefitinib resistance. | Gefitinib | epithelial membrane protein 1 | Homo sapiens |
| 7 | This report suggests the role of the adhesion molecule, EMP-1, as a biomarker of gefitinib clinical resistance, and further suggests a probable cross-talk between this molecule and the EGFR signaling pathway. | Gefitinib | epithelial membrane protein 1 | Homo sapiens |