Title : Asp578 in LEU4p is one of the key residues for leucine feedback inhibition release in sake yeast.

Pub. Date : 2005 Jul

PMID : 16041129






2 Functional Relationships(s)
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1 We identified a new mutation, Asp578Tyr, in alpha-isopropylmalate synthase (a LEU4 gene product) that releases leucine feedback inhibition and causes hyperproduction of isoamyl alcohol (i-AmOH) in sake yeast. isopentyl alcohol 2-isopropylmalate synthase LEU4 Saccharomyces cerevisiae S288C
2 We identified a new mutation, Asp578Tyr, in alpha-isopropylmalate synthase (a LEU4 gene product) that releases leucine feedback inhibition and causes hyperproduction of isoamyl alcohol (i-AmOH) in sake yeast. isopentyl alcohol 2-isopropylmalate synthase LEU4 Saccharomyces cerevisiae S288C