Title : Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo.

Pub. Date : 2005 Sep

PMID : 16006204






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Nitrogen-containing bisphosphonate drugs such as risedronate act by inhibiting farnesyl diphosphate synthase, thereby disrupting protein prenylation in osteoclasts. Nitrogen farnesyl diphosphate synthetase Mus musculus
2 Nitrogen-containing bisphosphonate drugs such as risedronate act by inhibiting farnesyl diphosphate synthase, thereby disrupting protein prenylation in osteoclasts. Diphosphonates farnesyl diphosphate synthetase Mus musculus
3 Nitrogen-containing bisphosphonate drugs such as risedronate act by inhibiting farnesyl diphosphate synthase, thereby disrupting protein prenylation in osteoclasts. Risedronic Acid farnesyl diphosphate synthetase Mus musculus