Title : Platelet-activating factor (PAF) involvement in acetaminophen-induced liver toxicity and regeneration.

Pub. Date : 2005 Aug

PMID : 15995853






1 Functional Relationships(s)
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1 The administration of a toxic dose of acetaminophen (3.5 g/kg) in rats caused acute hepatic injury, as evident by alterations of biochemical (serum enzymes: ALT, AST and ALP) and liver histopathological (degree of inflammation and apoptosis) indices between 20 and 40 h post-treatment. Acetaminophen PDZ and LIM domain 3 Rattus norvegicus