Title : Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators.

Pub. Date : 2005 Jul 22

PMID : 15911620






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Glucose deprivation rapidly increases the interaction between ASK1 and JIP3, and the consequently activated ASK1 phosphorylates SEK1 on the Thr-261 residue. Threonine mitogen-activated protein kinase kinase kinase 5 Homo sapiens
2 Glucose deprivation rapidly increases the interaction between ASK1 and JIP3, and the consequently activated ASK1 phosphorylates SEK1 on the Thr-261 residue. Threonine mitogen-activated protein kinase kinase kinase 5 Homo sapiens
3 Dissociated Akt1 binds to SEK1 and ASK1 and inhibits their enzyme activity by phosphorylating SEK1 on the Ser-80 residue and ASK1 on the Ser-83 residue. Serine mitogen-activated protein kinase kinase kinase 5 Homo sapiens