Title : Radiation resistance in a doxorubicin-resistant human fibrosarcoma cell line.

Pub. Date : 1992 Jun

PMID : 1590273






1 Functional Relationships(s)
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1 Using soft-agar colony formation after graded doses of x-rays as an endpoint, HT1080/DR4 had an increased D0 (D0 = 2.1 Gy) and a broader initial shoulder (n = 2.7, Dq = 2.1 Gy) than the parental HT1080 line (D0 = 0.7, Gy, n = 1.2, Dq = 0.3 Gy), suggesting that HT1080/DR4 has an increased capacity to repair radiation-induced DNA damage. Agar major histocompatibility complex, class II, DR beta 4 Homo sapiens