Pub. Date : 2005 Jun
PMID : 15901697
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AtzF, allophanate hydrolase, is a recently discovered member of the amidase signature family that catalyzes the terminal reaction during metabolism of s-triazine ring compounds by bacteria. | Triazines | atzF | Pseudomonas sp. ADP |
| 2 | Purified AtzF hydrolyzed allophanate with a k(cat)/K(m) of 1.1 x 10(4) s(-1) M(-1), and 2 mol of ammonia was released per mol allophanate. | allophanic acid | atzF | Pseudomonas sp. ADP |
| 3 | Purified AtzF hydrolyzed allophanate with a k(cat)/K(m) of 1.1 x 10(4) s(-1) M(-1), and 2 mol of ammonia was released per mol allophanate. | Ammonia | atzF | Pseudomonas sp. ADP |
| 4 | AtzF reacts with malonamate and hydroxylamine to generate malonohydroxamate, potentially derived from hydroxylamine capture of an enzyme-tethered acyl group. | malonamic acid | atzF | Pseudomonas sp. ADP |
| 5 | AtzF reacts with malonamate and hydroxylamine to generate malonohydroxamate, potentially derived from hydroxylamine capture of an enzyme-tethered acyl group. | Hydroxylamine | atzF | Pseudomonas sp. ADP |
| 6 | AtzF reacts with malonamate and hydroxylamine to generate malonohydroxamate, potentially derived from hydroxylamine capture of an enzyme-tethered acyl group. | malonohydroxamate | atzF | Pseudomonas sp. ADP |
| 7 | AtzF reacts with malonamate and hydroxylamine to generate malonohydroxamate, potentially derived from hydroxylamine capture of an enzyme-tethered acyl group. | Hydroxylamine | atzF | Pseudomonas sp. ADP |
| 8 | The identity of a putative serine nucleophile was probed using phenyl phosphorodiamidate that was shown to be a time-dependent inhibitor of AtzF. | Phenyl phosphorodiamidate | atzF | Pseudomonas sp. ADP |
| 9 | Thus, AtzF affects the cleavage of three carbon-to-nitrogen bonds via a mechanism similar to that of enzymes catalyzing single-amide-bond cleavage reactions. | Carbon | atzF | Pseudomonas sp. ADP |
| 10 | Thus, AtzF affects the cleavage of three carbon-to-nitrogen bonds via a mechanism similar to that of enzymes catalyzing single-amide-bond cleavage reactions. | Nitrogen | atzF | Pseudomonas sp. ADP |
| 11 | Thus, AtzF affects the cleavage of three carbon-to-nitrogen bonds via a mechanism similar to that of enzymes catalyzing single-amide-bond cleavage reactions. | Amides | atzF | Pseudomonas sp. ADP |