Pub. Date : 2005 Jun 17
PMID : 15883038
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Within this pathway, Disabled 1 (Dab1) serves as an intracellular adaptor that is tyrosine phosphorylated when Reelin, a secreted glycoprotein, binds to the lipoprotein receptors VLDLR and ApoER2 on the surface of neurons. | Tyrosine | very low density lipoprotein receptor | Homo sapiens |
2 | Here, we show that the phosphoinositide-binding region within Dab1 PTB domain is required for membrane localization and basal tyrosine phosphorylation of Dab1 independently of VLDLR and ApoER2. | Phosphatidylinositols | very low density lipoprotein receptor | Homo sapiens |