Pub. Date : 2005 Apr 7
PMID : 15735738
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreatment with [6]-gingerol resulted in a decrease in both TPA-induced DNA binding and transcriptional activities of NF-kappaB through suppression of IkappaBalpha degradation and p65 nuclear translocation. | gingerol | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 2 | Pretreatment with [6]-gingerol resulted in a decrease in both TPA-induced DNA binding and transcriptional activities of NF-kappaB through suppression of IkappaBalpha degradation and p65 nuclear translocation. | Tetradecanoylphorbol Acetate | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 3 | Phosphorylation of both IkappaBalpha and p65 was substantially blocked by [6]-gingerol. | gingerol | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 4 | In addition, [6]-gingerol inhibited TPA-stimulated interaction of phospho-p65-(Ser-536) with cAMP response element binding protein-binding protein, a transcriptional coactivator of NF-kappaB. | gingerol | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 5 | In addition, [6]-gingerol inhibited TPA-stimulated interaction of phospho-p65-(Ser-536) with cAMP response element binding protein-binding protein, a transcriptional coactivator of NF-kappaB. | Tetradecanoylphorbol Acetate | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 6 | In addition, [6]-gingerol inhibited TPA-stimulated interaction of phospho-p65-(Ser-536) with cAMP response element binding protein-binding protein, a transcriptional coactivator of NF-kappaB. | Serine | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 7 | In addition, [6]-gingerol inhibited TPA-stimulated interaction of phospho-p65-(Ser-536) with cAMP response element binding protein-binding protein, a transcriptional coactivator of NF-kappaB. | Cyclic AMP | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |