Title : An aminoacyl-tRNA synthetase with a defunct editing site.

Pub. Date : 2005 Mar 1

PMID : 15723544






1 Functional Relationships(s)
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1 Studies comparing Escherichia coli and hs mt LeuRS reveal that the proofreading activity of the mt enzyme is disrupted by these sequence changes, as significant levels of Ile-tRNA(Leu) are formed in the presence of high concentrations of the noncognate amino acid. ile-trna leucyl-tRNA synthetase 2, mitochondrial Homo sapiens