Pub. Date : 2005 Apr 8
PMID : 15695511
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The astroglial water channel aquaporin-4 (AQP4) facilitates water movement into and out of brain parenchyma. | Water | aquaporin 4 | Mus musculus |
| 2 | The astroglial water channel aquaporin-4 (AQP4) facilitates water movement into and out of brain parenchyma. | Water | aquaporin 4 | Mus musculus |
| 3 | The astroglial water channel aquaporin-4 (AQP4) facilitates water movement into and out of brain parenchyma. | Water | aquaporin 4 | Mus musculus |
| 4 | The astroglial water channel aquaporin-4 (AQP4) facilitates water movement into and out of brain parenchyma. | Water | aquaporin 4 | Mus musculus |
| 5 | AQP4-deficient mice had remarkably lower intracranial pressure (9 +/- 1 versus 25 +/- 5 cm H2O) and brain water accumulation (2 +/- 1 versus 9 +/- 1 microl) at 30 h, and improved survival (80 versus 0% survival) at 60 h, through comparable CSF bacterial and white cell counts. | Water | aquaporin 4 | Mus musculus |
| 6 | AQP4-deficient mice had remarkably lower intracranial pressure (9 +/- 1 versus 25 +/- 5 cm H2O) and brain water accumulation (2 +/- 1 versus 9 +/- 1 microl) at 30 h, and improved survival (80 versus 0% survival) at 60 h, through comparable CSF bacterial and white cell counts. | Water | aquaporin 4 | Mus musculus |
| 7 | AQP4 protein was strongly up-regulated in meningitis, resulting in a approximately 5-fold higher water permeability (P(f)) across the blood-brain barrier compared with non-infected wild type mice. | Water | aquaporin 4 | Mus musculus |