Title : Receptor-induced switch in site-site cooperativity during iron release by transferrin.

Pub. Date : 1992 Apr 28

PMID : 1567848






1 Functional Relationships(s)
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1 Iron removal by PPi from the N- and C-terminal binding sites of both free and receptor-complexed transferrin, when the partner site remains occupied with kinetically inert Co(III), has been studied at pH 7.4 and 5.6, at 25 degrees C. At extracellular pH, 7.4, the C-terminal site of free mixed-metal proteins is slightly more labile than its N-terminal counterpart in releasing iron to 0.05 M PPi. Iron mitochondrially encoded cytochrome c oxidase III Homo sapiens