Title : Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cells.

Pub. Date : 1992 Apr 15

PMID : 1565614






1 Functional Relationships(s)
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1 The ASM activities in these cells were less than 4% of mean normal levels, and, consequently, they accumulated approximately 3-fold elevated levels of sphingomyelin. Sphingomyelins sphingomyelin phosphodiesterase 1 Homo sapiens