Pub. Date : 2005 Feb 4
PMID : 15629441
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Infection of isolated neonatal cardiomyocytes with an adenoviral vector expressing CaMKIIdelta3 (AdCaMKIIdelta3) induced the activation of ASK1, while KN93, an inhibitor of CaMKII, inhibited phenylephrine-induced ASK1 activation. | Phenylephrine | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 2 | Infection of cardiomyocytes with an adenoviral vector expressing a dominant negative mutant of ASK1 (AdASK(KM)) inhibited the CaMKIIdelta3-induced hypertrophic responses. | adask | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 3 | These results indicate that CaMKIIdelta3 induces cardiomyocyte hypertrophy mediated through ASK1-NF-kappaB signal transduction pathway. | camkiidelta3 | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |