Title : Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors.

Pub. Date : 2005 Feb 18

PMID : 15574424






9 Functional Relationships(s)
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Protein Name
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1 Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors. Cyclic ADP-Ribose bone marrow stromal cell antigen 1 Homo sapiens
2 Cyclic ADP-ribose (cADPR) is an intracellular calcium mobilizer generated from NAD(+) by the ADP-ribosyl cyclases CD38 and BST-1. Cyclic ADP-Ribose bone marrow stromal cell antigen 1 Homo sapiens
3 Cyclic ADP-ribose (cADPR) is an intracellular calcium mobilizer generated from NAD(+) by the ADP-ribosyl cyclases CD38 and BST-1. Calcium bone marrow stromal cell antigen 1 Homo sapiens
4 Cyclic ADP-ribose (cADPR) is an intracellular calcium mobilizer generated from NAD(+) by the ADP-ribosyl cyclases CD38 and BST-1. NAD bone marrow stromal cell antigen 1 Homo sapiens
5 Influx of paracrinally generated cADPR into clonogenic HP was mediated by a concentrative, nitrobenzylthioinosine- and dipyridamole-inhibitable nucleoside transporter, this providing a possible explanation to the effectiveness of the hormone-like concentrations of the cyclic nucleotide measured in the medium conditioned by BST-1(+) feeders. 4-nitrobenzylthioinosine bone marrow stromal cell antigen 1 Homo sapiens
6 Influx of paracrinally generated cADPR into clonogenic HP was mediated by a concentrative, nitrobenzylthioinosine- and dipyridamole-inhibitable nucleoside transporter, this providing a possible explanation to the effectiveness of the hormone-like concentrations of the cyclic nucleotide measured in the medium conditioned by BST-1(+) feeders. Dipyridamole bone marrow stromal cell antigen 1 Homo sapiens
7 Influx of paracrinally generated cADPR into clonogenic HP was mediated by a concentrative, nitrobenzylthioinosine- and dipyridamole-inhibitable nucleoside transporter, this providing a possible explanation to the effectiveness of the hormone-like concentrations of the cyclic nucleotide measured in the medium conditioned by BST-1(+) feeders. Nucleotides, Cyclic bone marrow stromal cell antigen 1 Homo sapiens
8 These results suggest that the BST-1-catalyzed generation of extracellular cADPR, followed by the concentrative uptake of the cyclic nucleotide by HP, may be physiologically relevant in normal hemopoiesis. Nucleotides, Cyclic bone marrow stromal cell antigen 1 Homo sapiens
9 These results suggest that the BST-1-catalyzed generation of extracellular cADPR, followed by the concentrative uptake of the cyclic nucleotide by HP, may be physiologically relevant in normal hemopoiesis. Hematoporphyrins bone marrow stromal cell antigen 1 Homo sapiens