Title : New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice.

Pub. Date : 2004

PMID : 15561413






8 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Water aquaporin 4 Mus musculus
2 Aquaporin-4 (AQP4) is the major water channel in the CNS. Water aquaporin 4 Mus musculus
3 Aquaporin-4 (AQP4) is the major water channel in the CNS. Water aquaporin 4 Mus musculus
4 Primary cultures of astrocytes from AQP4-null mice have greatly reduced osmotic water permeability compared with wild-type astrocytes, indicating that AQP4 is the principal water channel in these cells. Water aquaporin 4 Mus musculus
5 Primary cultures of astrocytes from AQP4-null mice have greatly reduced osmotic water permeability compared with wild-type astrocytes, indicating that AQP4 is the principal water channel in these cells. Water aquaporin 4 Mus musculus
6 Primary cultures of astrocytes from AQP4-null mice have greatly reduced osmotic water permeability compared with wild-type astrocytes, indicating that AQP4 is the principal water channel in these cells. Water aquaporin 4 Mus musculus
7 In contrast, brain swelling and clinical outcome are worse in AQP4-null mice in models of vasogenic (fluid leak) edema caused by freeze-injury and brain tumor, probably due to impaired AQP4-dependent brain water clearance. Water aquaporin 4 Mus musculus
8 In contrast, brain swelling and clinical outcome are worse in AQP4-null mice in models of vasogenic (fluid leak) edema caused by freeze-injury and brain tumor, probably due to impaired AQP4-dependent brain water clearance. Water aquaporin 4 Mus musculus