Pub. Date : 2004
PMID : 15561413
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. | Water | aquaporin 4 | Mus musculus |
2 | Aquaporin-4 (AQP4) is the major water channel in the CNS. | Water | aquaporin 4 | Mus musculus |
3 | Aquaporin-4 (AQP4) is the major water channel in the CNS. | Water | aquaporin 4 | Mus musculus |
4 | Primary cultures of astrocytes from AQP4-null mice have greatly reduced osmotic water permeability compared with wild-type astrocytes, indicating that AQP4 is the principal water channel in these cells. | Water | aquaporin 4 | Mus musculus |
5 | Primary cultures of astrocytes from AQP4-null mice have greatly reduced osmotic water permeability compared with wild-type astrocytes, indicating that AQP4 is the principal water channel in these cells. | Water | aquaporin 4 | Mus musculus |
6 | Primary cultures of astrocytes from AQP4-null mice have greatly reduced osmotic water permeability compared with wild-type astrocytes, indicating that AQP4 is the principal water channel in these cells. | Water | aquaporin 4 | Mus musculus |
7 | In contrast, brain swelling and clinical outcome are worse in AQP4-null mice in models of vasogenic (fluid leak) edema caused by freeze-injury and brain tumor, probably due to impaired AQP4-dependent brain water clearance. | Water | aquaporin 4 | Mus musculus |
8 | In contrast, brain swelling and clinical outcome are worse in AQP4-null mice in models of vasogenic (fluid leak) edema caused by freeze-injury and brain tumor, probably due to impaired AQP4-dependent brain water clearance. | Water | aquaporin 4 | Mus musculus |