Title : Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle.

Pub. Date : 2005 Mar

PMID : 15548569






2 Functional Relationships(s)
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1 Interestingly, myotubes expressing RyR3 always had significantly higher [Ca(2+)](r) and lower caffeine EC(50) than did cells expressing RyR1. caffeine ec ryanodine receptor 3 Homo sapiens
2 Although some of the increased sensitivity of RyR3 to caffeine could be attributed to the higher [Ca(2+)](r) in RyR3-expressing cells, studies of [(3)H]ryanodine binding demonstrated intrinsic differences in caffeine sensitivity between RyR1 and RyR3. Caffeine ryanodine receptor 3 Homo sapiens