Pub. Date : 2005 Mar
PMID : 15525791
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65. | ethyl pyruvate | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 2 | Taken together, these results suggest that ethyl pyruvate inhibits DNA-binding by covalently modifying p65 at Cys(38). | ethyl pyruvate | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 3 | Taken together, these results suggest that ethyl pyruvate inhibits DNA-binding by covalently modifying p65 at Cys(38). | Cysteine | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 4 | We conclude that some of the beneficial anti-inflammatory effects of ethyl pyruvate may be due to modification of p65, thereby inhibiting signaling via the NF-kappaB pathway. | ethyl pyruvate | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |