Pub. Date : 1992 Feb 15
PMID : 1540140
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism. | Sphingosine | LOC100009319 | Oryctolagus cuniculus |
2 | Furthermore, the hydrolytic action of exogenously added phospholipase C (from Clostridium perfringens) on platelet membrane phospholipids was dose-dependently enhanced by pretreatment of the platelets with sphingosine. | Phospholipids | LOC100009319 | Oryctolagus cuniculus |
3 | Furthermore, the hydrolytic action of exogenously added phospholipase C (from Clostridium perfringens) on platelet membrane phospholipids was dose-dependently enhanced by pretreatment of the platelets with sphingosine. | Sphingosine | LOC100009319 | Oryctolagus cuniculus |
4 | These results imply that sphingosine, at relatively low concentrations, brings about hyperaggregability of the platelets by the agonists employed, probably owing to enhancement of the phospholipase C activity. | Sphingosine | LOC100009319 | Oryctolagus cuniculus |