Title : Effects of ethanol and phenobarbital treatments on the pharmacokinetics of toluene in rats.

Pub. Date : 1992 Feb

PMID : 1536817






1 Functional Relationships(s)
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1 The Michaelis constant (Km) and the maximum rate of metabolic excretion in urine during six hours exposure (Vmax) of isozymes involved in the excretion of toluene metabolites were calculated, and correlated with the subtypes of cytochrome P-450. Toluene cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus