Title : Hsp90 chaperones wild-type p53 tumor suppressor protein.

Pub. Date : 2004 Nov 19

PMID : 15358769






1 Functional Relationships(s)
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1 Interestingly, Hsp90 in an ATP-dependent manner can positively modulate p53 DNA binding after incubation at physiological temperature of 37 degrees C. Other recombinant human chaperones from Hsp70 and Hsp40 families were not able to efficiently substitute Hsp90 in this reaction. Adenosine Triphosphate DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 Homo sapiens