Title : IL-1 increases phospholipase A2 activity, expression of phospholipase A2-activating protein, and release of linoleic acid from the murine T helper cell line EL-4.

Pub. Date : 1992 Jan 1

PMID : 1530793






6 Functional Relationships(s)
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1 IL-1 increases phospholipase A2 activity, expression of phospholipase A2-activating protein, and release of linoleic acid from the murine T helper cell line EL-4. Linoleic Acid interleukin 1 complex Mus musculus
2 The consequence of the elevated PLA2 activity was examined by analysis of the fatty acids released from IL-1-treated cells. Fatty Acids interleukin 1 complex Mus musculus
3 In EL-4 cells, IL-1 potentiates PMA-mediated release of IL-2 at suboptimal concentrations of PMA. Tetradecanoylphorbol Acetate interleukin 1 complex Mus musculus
4 In EL-4 cells, IL-1 potentiates PMA-mediated release of IL-2 at suboptimal concentrations of PMA. Tetradecanoylphorbol Acetate interleukin 1 complex Mus musculus
5 Furthermore, the release of the unsaturated fatty acid linoleic acid or its metabolites may be of functional importance in IL-1-mediated IL-2 production by EL-4 cells. Fatty Acids, Unsaturated interleukin 1 complex Mus musculus
6 Furthermore, the release of the unsaturated fatty acid linoleic acid or its metabolites may be of functional importance in IL-1-mediated IL-2 production by EL-4 cells. Linoleic Acid interleukin 1 complex Mus musculus