Title : Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer.

Pub. Date : 2004 Aug

PMID : 15299075






2 Functional Relationships(s)
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1 Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Auristatin E transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens
2 To evaluate anti-TMEFF2 mAbs as potential ADCs, one mAb was conjugated to the cytotoxic agent auristatin E via a cathepsin B-sensitive valine-citrulline linker. Auristatin E transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens