Title : Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: role of Rho-dependent mechanisms.

Pub. Date : 2004 Oct

PMID : 15281089






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Rho-mediated activation of its downstream target, Rho-kinase, induced phosphorylation of Rho-kinase effector EC MLC phosphatase (MYPT1) at Thr(696) and Thr(850) resulting in MYPT1 inactivation. Threonine protein phosphatase 1 regulatory subunit 12A Homo sapiens
2 Rho-mediated activation of its downstream target, Rho-kinase, induced phosphorylation of Rho-kinase effector EC MLC phosphatase (MYPT1) at Thr(696) and Thr(850) resulting in MYPT1 inactivation. Threonine protein phosphatase 1 regulatory subunit 12A Homo sapiens
3 Rho-mediated activation of its downstream target, Rho-kinase, induced phosphorylation of Rho-kinase effector EC MLC phosphatase (MYPT1) at Thr(696) and Thr(850) resulting in MYPT1 inactivation. Threonine protein phosphatase 1 regulatory subunit 12A Homo sapiens
4 Rho-mediated activation of its downstream target, Rho-kinase, induced phosphorylation of Rho-kinase effector EC MLC phosphatase (MYPT1) at Thr(696) and Thr(850) resulting in MYPT1 inactivation. Threonine protein phosphatase 1 regulatory subunit 12A Homo sapiens
5 Inhibition of Rho-kinase by Y27632 abolished ND-induced MYPT1 phosphorylation, MLC phosphorylation, and stress fiber formation. Y 27632 protein phosphatase 1 regulatory subunit 12A Homo sapiens