Title : Defective acidification of intracellular organelles results in aberrant secretion of cathepsin D in cancer cells.

Pub. Date : 2004 Sep 17

PMID : 15258139






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It accumulated mainly in late endosomes and/or lysosomes as a complex with its ligand (proCD or intermediate CD), as evidenced by its co-localization with both CD and LAMP-2, a late endosome/lysosome marker. Cadmium lysosomal associated membrane protein 2 Homo sapiens
2 It accumulated mainly in late endosomes and/or lysosomes as a complex with its ligand (proCD or intermediate CD), as evidenced by its co-localization with both CD and LAMP-2, a late endosome/lysosome marker. Cadmium lysosomal associated membrane protein 2 Homo sapiens
3 NH(4)Cl induced similar receptor redistribution into LAMP-2-positive structures in acidification-competent cells but not in MCF-7 cells. (4)cl lysosomal associated membrane protein 2 Homo sapiens