Pub. Date : 2004
PMID : 15254665
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation. | Fluorouracil | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 2 | The effect of tamoxifen (TAM), lanreotide (LAN) and 5-fluorouracil (5-FU), given separately or together, on p65 gene expression in murine Colon 38 cancer was investigated by RT-PCR method. | Fluorouracil | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 3 | The effect of tamoxifen (TAM), lanreotide (LAN) and 5-fluorouracil (5-FU), given separately or together, on p65 gene expression in murine Colon 38 cancer was investigated by RT-PCR method. | Fluorouracil | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 4 | After a combined treatment with TAM and LAN a percentage of p65 positive cases was similar to that of the control group and equaled approximately 60%. | Tamoxifen | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 5 | In the group with 5-FU alone the expression of p65 was present in about 80% of samples. | Fluorouracil | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 6 | In the group treated with a combination of TAM and 5-FU all analyzed cases showed the presence of p65 gene expression. | Tamoxifen | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 7 | In the group treated with a combination of TAM and 5-FU all analyzed cases showed the presence of p65 gene expression. | Fluorouracil | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |
| 8 | Based on these findings we conclude that p65 gene expression in murine Colon 38 cancer tissues can be modulated via chemotherapy (5-FU) and also via hormonal modulation (TAM and LAN). | Fluorouracil | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Mus musculus |