Pub. Date : 2004 Aug 15
PMID : 15246877
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | S-nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1. | Nitric Oxide | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 2 | S-nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1. | Superoxides | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 3 | N2O3-dependent S-nitrosation of Trx at approximately 2-fold of NO excess compared to the superoxide amount resulted in dissociation and activation of apoptosis signal regulating kinase 1 (ASK1). | Dinitrogen trioxide | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 4 | N2O3-dependent S-nitrosation of Trx at approximately 2-fold of NO excess compared to the superoxide amount resulted in dissociation and activation of apoptosis signal regulating kinase 1 (ASK1). | Dinitrogen trioxide | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 5 | N2O3-dependent S-nitrosation of Trx at approximately 2-fold of NO excess compared to the superoxide amount resulted in dissociation and activation of apoptosis signal regulating kinase 1 (ASK1). | Superoxides | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 6 | N2O3-dependent S-nitrosation of Trx at approximately 2-fold of NO excess compared to the superoxide amount resulted in dissociation and activation of apoptosis signal regulating kinase 1 (ASK1). | Superoxides | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |
| 7 | However, approximately 4-fold of NO excess compared to a superoxide production preserved the level of dissociated ASK1 but decreased its activity due to the enzyme S-nitrosation. | Superoxides | mitogen-activated protein kinase kinase kinase 5 | Homo sapiens |