Title : Disruption of Rho signal transduction upon cell detachment.

Pub. Date : 2004 Jul 15

PMID : 15226371






2 Functional Relationships(s)
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Protein Name
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1 Characterization of Rho-kinase substrates revealed that diphosphorylation of MLC at Thr-18 and Ser-19 (ppMLC(T18/S19)) and phosphorylation of the myosin-binding subunit (MBS) of myosin phosphatase at Thr-853 (pMBS(T853)) were mostly Rho and Rho-kinase dependent in attached fibroblasts. Threonine protein phosphatase 1 regulatory subunit 12A Homo sapiens
2 Characterization of Rho-kinase substrates revealed that diphosphorylation of MLC at Thr-18 and Ser-19 (ppMLC(T18/S19)) and phosphorylation of the myosin-binding subunit (MBS) of myosin phosphatase at Thr-853 (pMBS(T853)) were mostly Rho and Rho-kinase dependent in attached fibroblasts. (4-sulfophenyl)mercury protein phosphatase 1 regulatory subunit 12A Homo sapiens