Title : NF-kappaB inducing kinase activates NF-kappaB transcriptional activity independently of IkappaB kinase gamma through a p38 MAPK-dependent RelA phosphorylation pathway.

Pub. Date : 2004 Sep

PMID : 15212763






1 Functional Relationships(s)
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1 Functional analysis demonstrated that Ad5NIK-induced NF-kappaB transcriptional activity, IL-6 mRNA expression and RelA phosphorylation are inhibited by the p38 inhibitor SB203580, suggesting a role for this MAPK in NIK signaling to NF-kappaB. SB 203580 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus