Title : Direct binding of apoptosis signal-regulating kinase 1 to retinoblastoma protein: novel links between apoptotic signaling and cell cycle machinery.

Pub. Date : 2004 Sep 10

PMID : 15210709






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 An LXCXE motif on ASK1 was required for Rb binding; this correlated with increased E2F1 transcriptional activity and up-regulation of the proapoptotic protein p73. Rubidium mitogen-activated protein kinase kinase kinase 5 Homo sapiens