Pub. Date : 2004 May-Jun
PMID : 15191400
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Auranofin, an antirheumatic gold compound, is an inhibitor of selenocysteine enzymes, such as thioredoxin reductase and glutathione peroxidase. | Auranofin | peroxiredoxin 5 | Rattus norvegicus |
| 2 | There was significantly less thioredoxin reductase activity in rat liver extracts, whereas the level of glutathione activity remained unchanged, demonstrating that the dose of auranofin used was able to selectively inhibit one of these enzyme systems. | Auranofin | peroxiredoxin 5 | Rattus norvegicus |