Title : In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography.

Pub. Date : 2004 Jun 1

PMID : 15150578






3 Functional Relationships(s)
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1 Here, we describe the validation of [(18)F]fluoroetanidazole ([(18)F]FETA) as a tumour hypoxia marker by positron emission tomography (PET). fluoroetanidazole ATPase, class I, type 8B, member 5 Mus musculus
2 [(18)F]FETA, with an octanol-water partition coefficient of 0.16+/-0.01, was selectively retained by RIF-1 cells under hypoxia compared to air (3.4- to 4.3-fold at 60-120 min). Octanols ATPase, class I, type 8B, member 5 Mus musculus
3 [(18)F]FETA, with an octanol-water partition coefficient of 0.16+/-0.01, was selectively retained by RIF-1 cells under hypoxia compared to air (3.4- to 4.3-fold at 60-120 min). Water ATPase, class I, type 8B, member 5 Mus musculus